[HTML][HTML] MATria: a unified centrality algorithm

T Cickovski, V Aguiar-Pulido, G Narasimhan - BMC bioinformatics, 2019 - Springer
… three biological networks, we demonstrate evident and balanced correlations with the results
of these k algorithms… We build on a prior algorithm called ATRIA [15], which reduced bias in …

Identification of functional lncRNAs in atrial fibrillation by integrative analysis of the lncRNA‐mRNA network based on competing endogenous RNAs hypothesis

C Qian, H Li, D Chang, B Wei… - Journal of cellular …, 2019 - Wiley Online Library
… of novel diagnostic biomarkers or therapeutic targets. … centrality in network. The BC of node
i could be defined as: … basic topological features of a biological network. As shown in Figure 2…

[HTML][HTML] Identification of critical connectors in the directed reaction-centric graphs of microbial metabolic networks

EY Kim, D Ashlock, SH Yoon - BMC bioinformatics, 2019 - Springer
biological networks depends on centrality metrics quantifying individual nodes’ importance
in a network… To investigate the local role of a node, we developed a novel metric, cascade …

[HTML][HTML] Directed networks as a novel way to describe and analyze cardiac excitation: directed graph mapping

N Vandersickel, E Van Nieuwenhuyse… - Frontiers in …, 2019 - frontiersin.org
networks to the heart for each driving mechanism of cardiac arrhythmias in both the atria and
… of DG mapping in the atria, we analyzed 31 clinical cases of atrial tachycardia. Regular AT …

[HTML][HTML] Reviewing atrial fibrillation pathophysiology from a network medicine perspective: the relevance of structural remodeling, inflammation, and the immune …

ILF Martins, FVS Almeida, KP Souza, FCF Brito… - Life, 2023 - mdpi.com
… in biological processes. The number of interaction partners constitutes the degree of centrality,
being a local centrality … Thus, this review aims to present network medicine as a novel

Bioinformatics‐based analysis of mechanistic differences in vascular endothelial injury ischemic stroke induced by atrial fibrillation and atherosclerosis

J Li, R Yang, S Wang, Z Shen, B Wu… - Journal of …, 2023 - Wiley Online Library
… Clique Centrality algorithm ranking … biological network is heterogeneous, it was reasonable
to use more than one method to obtain essential proteins. Thus, we used the MCC algorithm

Meta-analysis of transcriptomic data reveals pathophysiological modules involved with atrial fibrillation

R Haas Bueno, M Recamonde-Mendoza - Molecular Diagnosis & Therapy, 2020 - Springer
… Two measures of centrality were evaluated to determine the … the represented processes
in the biological network [43]. Of … methods, resulting in novel AF biomarker candidate genes. …

Identification of atrial fibrillation-related circular RNAs and constructing the integrative regulatory network of circular RNAs, microRNAs and mRNAs by bioinformatics …

Z Zhai, T Qin, F Liu, L Han, H Zhou, Q Li… - … and Molecular Biology, 2020 - cellmolbiol.org
… of centrality. A node with higher betweenness centrality would have more control over the
network… In addition, identification new circRNAs relating to atrial fibrillation could provide novel

[HTML][HTML] Identification and validation of aging-related genes in atrial fibrillation

Y Zhou, C Sun, Y Ma, Y Huang, K Wu, S Huang, Q Lin… - Plos one, 2023 - journals.plos.org
… related genes and AF holds the potential to unveil novel therapeutic targets for this disease.
… by Maximal Clique Centrality (MCC) algorithm. MCC identifies central nodes in a network by …

[PDF][PDF] Whole-Atria Optical Analysis of Transverse-Axial Tubule System for Identification of Vulnerable “Hot Spots” for Arrhythmia Development

LN Ratajczyk, AK Irwin, D Lang, AV Glukhov - Biophysical Journal, 2020 - cell.com
… A graph node centrality analysis showed that 22 signaling molecules primarily in MAPK …
Multiple stacks were generated by adjusting focal plane to overcome the atrial curvature. A novel